diff --git a/src/channels/mod.rs b/src/channels/mod.rs
index 8e927cac1..4648391f9 100644
--- a/src/channels/mod.rs
+++ b/src/channels/mod.rs
@@ -1814,7 +1814,17 @@ async fn process_channel_message(
         msg
     };
 
-    let target_channel = ctx.channels_by_name.get(&msg.channel).cloned();
+    let target_channel = ctx
+        .channels_by_name
+        .get(&msg.channel)
+        .or_else(|| {
+            // Multi-room channels use "name:qualifier" format (e.g. "matrix:!roomId");
+            // fall back to base channel name for routing.
+            msg.channel
+                .split_once(':')
+                .and_then(|(base, _)| ctx.channels_by_name.get(base))
+        })
+        .cloned();
     if let Err(err) = maybe_apply_runtime_config_update(ctx.as_ref()).await {
         tracing::warn!("Failed to apply runtime config update: {err}");
     }